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Category:2015 films
Category:Telugu-language films
Category:Indian filmsEfficacy of ACTH4-10 and PTH1-34 in the treatment of Cushing's disease.
The long-acting adrenocorticotropic hormone (ACTH) derivative, ACTH4-10, and the long-acting parathyroid hormone (PTH) derivative, PTH1-34, were compared with each other and with metyrapone in a 1-yr prospective study of the treatment of Cushing's disease. Fifty patients received daily subcutaneous injections of either ACTH4-10 (100 micrograms) or PTH1-34 (100 micrograms). Plasma cortisol responses to ACTH4-10 were significantly greater than those to PTH1-34 (P less than 0.05) and PTH1-34 were more efficacious than ACTH4-10 (P less than 0.05). Seventy percent of patients were cured (cortisol levels were less than 10 micrograms/dl and less than 2 micrograms/dl after dexamethasone) with ACTH4-10 and PTH1-34, respectively, at 1 year. None of the patients treated with metyrapone had total remission. ACTH4-10 was more effective than PTH1-34 in maintaining remission at 1 yr. ACTH4-10 was associated with a reduced frequency of treatment-associated adverse effects.Want to make use of your out-of-date gift card? In this tutorial we’ll be looking at how to cash out any gift card balance that you might have. You can find out how to redeem and withdraw the balance from most popular cards.
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